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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | SO | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Mauro Pérez* | 231 | 2022 | |
| 2 | Ryan Howard | 215 | 2012 | |
| 2 | Bob Austin* | 215 | 2017 | |
| 4 | Luis Sánchez | 212 | 2018 | |
| 5 | Mauro Pérez* | 208 | 2020 | |
| 6 | Ryan Howard | 202 | 2013 | |
| 7 | Ryan Howard | 195 | 2011 | |
| 8 | Luis Sánchez | 193 | 2015 | |
| 9 | Austin Riley# | 192 | 2030 | |
| 10 | Mauro Pérez* | 190 | 2021 | |
| 11 | José González# | 189 | 2026 | |
| 12 | Ryan Howard | 182 | 2010 | |
| 13 | Bob Austin* | 181 | 2016 | |
| 14 | Mauro Pérez* | 178 | 2019 | |
| 14 | Júlio Pérez# | 178 | 2028 | |
| 14 | Derrek Lee | 178 | 2002 | |
| 17 | Luis Sánchez | 177 | 2016 | |
| 18 | Austin Riley# | 173 | 2029 | |
| 19 | Lee Orr# | 171 | 2029 | |
| 19 | Brant Brown | 171 | 2002 | |
| 19 | Anthony Rizzo | 171 | 2015 | |
| 19 | Bob Austin* | 171 | 2015 | |
| 23 | Manuel Márquez# | 170 | 2029 | |
| 24 | Mauro Pérez* | 169 | 2018 | |
| 25 | Carlos Pena | 168 | 2002 | |
| 25 | Luis Sánchez | 168 | 2014 | |
| 27 | Ryan Howard | 167 | 2006 | |
| 28 | Ryan Howard | 165 | 2009 | |
| 28 | Ryan Howard | 165 | 2008 | |
| 30 | Hiram Bocachica | 164 | 2002 | |
| 30 | Hiram Bocachica | 164 | 2003 | |
| 30 | Lee Orr# | 164 | 2030 | |
| 33 | Ryan Howard | 163 | 2007 | |
| 34 | Kevin Barker | 162 | 2003 | |
| 34 | Hiram Bocachica | 162 | 2004 | |
| 34 | Bob Lemcke# | 162 | 2021 | |
| 37 | Elmer Brown | 161 | 2026 | |
| 37 | Jeff Bagwell* | 161 | 2002 | |
| 39 | Bob Hamelin | 160 | 1999 | |
| 39 | Elmer Brown | 160 | 2021 | |
| 39 | Hank Blalock | 160 | 2011 | |
| 39 | Hee-Seop Choi | 160 | 2007 | |
| 39 | Augusto De La Cruz | 160 | 2015 | |
| 44 | Carlos Pena | 159 | 2003 | |
| 45 | Stan Ross | 158 | 2018 | |
| 46 | Francisco Cabrera* | 157 | 1997 | |
| 46 | Mauro Pérez* | 157 | 2008 | |
| 46 | Carlos Pena | 157 | 2004 | |
| 46 | Mauro Pérez* | 157 | 2014 | |
| 46 | Mauro Pérez* | 157 | 2017 | |
| 46 | Tom Árias# | 157 | 2027 | |
| 46 | Hee-Seop Choi | 157 | 2008 | |
| 53 | Manuel Márquez# | 156 | 2028 | |
| 53 | Mauro Pérez* | 156 | 2015 | |
| 53 | Carlos Pena | 156 | 2006 | |
| 56 | Joey Votto* | 155 | 2015 | |
| 56 | Juan Cortéz# | 155 | 2030 | |
| 56 | Eric Green | 155 | 2014 | |
| 56 | Nick Swisher | 155 | 2005 | |
| 60 | Al Hammond# | 154 | 2028 | |
| 60 | Henry Thompson# | 154 | 2021 | |
| 60 | Nick Swisher | 154 | 2010 | |
| 63 | Elmer Brown | 153 | 2023 | |
| 63 | Mark Teixeira* | 153 | 2016 | |
| 63 | Joey Votto* | 153 | 2021 | |
| 66 | Brian Daubach | 152 | 2001 | |
| 67 | Jeffrey Young# | 151 | 2031 | |
| 67 | John MacIvor# | 151 | 2029 | |
| 67 | Adam LaRoche | 151 | 2006 | |
| 67 | Bob Austin* | 151 | 2009 | |
| 71 | Tom Parkinson# | 150 | 2023 | |
| 71 | Nick Johnson | 150 | 2003 | |
| 71 | Nick Swisher | 150 | 2009 | |
| 71 | Mauro Pérez* | 150 | 2016 | |
| 71 | Arturo Vera# | 150 | 2030 | |
| 71 | Russ Davis | 150 | 2005 | |
| 77 | José González# | 149 | 2024 | |
| 77 | Ray Flowers | 149 | 2021 | |
| 77 | Anthony Rizzo | 149 | 2018 | |
| 77 | Juan Vázquez# | 149 | 2028 | |
| 81 | Jeff Bagwell* | 148 | 2000 | |
| 81 | Brian Daubach | 148 | 2000 | |
| 81 | César Morín# | 148 | 2030 | |
| 81 | Bob Austin* | 148 | 2011 | |
| 85 | Adam LaRoche | 147 | 2007 | |
| 85 | Paul Goldschmidt | 147 | 2020 | |
| 87 | Al Hammond# | 146 | 2026 | |
| 87 | Yun-ho Son# | 146 | 2031 | |
| 87 | Tom Clark# | 146 | 2027 | |
| 90 | Edmond George | 145 | 2020 | |
| 90 | José Osón | 145 | 2024 | |
| 90 | Adrian Gonzalez | 145 | 2013 | |
| 93 | Júlio Sánchez | 144 | 2012 | |
| 93 | Francisco Cabrera* | 144 | 1995 | |
| 93 | Mauro Pérez* | 144 | 2012 | |
| 93 | Chris Lange | 144 | 2003 | |
| 97 | Nick Johnson | 143 | 2002 | |
| 97 | Derrek Lee | 143 | 2001 | |
| 97 | Craig Lynch | 143 | 2018 | |
| 100 | Stan Ross | 142 | 2016 |
