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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | OAVG | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Archie Esparza# | .1899 | 2025-2031 | |
| 2 | Kerry Wood | .2025 | 1998-2007 | |
| 3 | David Robertson | .2056 | 2011-2023 | |
| 3 | Gilberto Martínez# | .2056 | 2025-2031 | |
| 5 | Victor Moret | .2079 | 2003-2016 | |
| 6 | Terrell Wade | .2118 | 1995-2010 | |
| 7 | Mo Sanford | .2176 | 1991-2005 | |
| 8 | Paul Hale# | .2199 | 2020-2031 | |
| 9 | Gregory Burke | .2222 | 2002-2013 | |
| 10 | Randy D Johnson | .2232 | 1988-2003 | |
| 11 | Roger Clemens* | .2234 | 1984-2006 | |
| 12 | Bob Jenkins* | .2242 | 2008-2023 | |
| 13 | Jake McGee | .2258 | 2015-2023 | |
| 14 | Rick Snow# | .2262 | 2026-2031 | |
| 15 | Pedro J Martinez | .2264 | 1992-2007 | |
| 16 | Mark Prior* | .2271 | 2002-2016 | |
| 17 | Scott Kazmir | .2282 | 2004-2019 | |
| 18 | Wilford Chambers* | .2285 | 2006-2025 | |
| 19 | Joe Sparks | .2294 | 2007-2019 | |
| 20 | Dellin Betances | .2318 | 2012-2028 | |
| 21 | Ebby Calvin LaLoosh | .2319 | 2007-2018 | |
| 22 | Brad Lidge | .2323 | 2002-2017 | |
| 23 | Juan Guzman* | .2330 | 1991-2005 | |
| 24 | Dan Wilkerson# | .2343 | 2023-2031 | |
| 25 | Javier Vazquez* | .2350 | 1998-2013 | |
| 26 | Jesús Enríquez | .2359 | 2001-2015 | |
| 27 | Hideo Nomo | .2363 | 1995-2003 | |
| 28 | James Ryan# | .2369 | 2017-2027 | |
| 28 | Jeff Sawyer | .2369 | 2006-2018 | |
| 30 | Ryan Dempster | .2372 | 1999-2007 | |
| 31 | Dave Dowden | .2374 | 2017-2027 | |
| 32 | Nathan Whalebelly | .2376 | 2015-2029 | |
| 32 | José Torres# | .2376 | 2026-2031 | |
| 34 | Bill Gill# | .2381 | 2023-2031 | |
| 35 | Toki Nagai | .2384 | 2004-2015 | |
| 35 | Scott Sanders | .2384 | 1993-2007 | |
| 35 | Juan Velázquez# | .2384 | 2025-2031 | |
| 38 | Santiago Herrera | .2386 | 2000-2018 | |
| 39 | Dan Woods# | .2387 | 2023-2031 | |
| 40 | Michael Hood | .2388 | 2002-2013 | |
| 40 | Ronald Moyer# | .2388 | 2023-2031 | |
| 42 | Greg Keagle | .2408 | 1996-2006 | |
| 42 | Wesley Wright | .2408 | 2013-2020 | |
| 44 | Gary Lefebvre | .2409 | 2002-2016 | |
| 45 | Rick Ankiel | .2410 | 1999-2015 | |
| 46 | Nolan Arnold | .2412 | 2011-2022 | |
| 47 | Lee Myers# | .2413 | 2019-2031 | |
| 48 | John Lambert# | .2414 | 2022-2031 | |
| 49 | Ramon J Martinez | .2417 | 1988-2002 | |
| 50 | Daron Maddox | .2418 | 2015-2027 | |
| 50 | Vicente Maldonado# | .2418 | 2025-2031 | |
| 52 | Carlos Jiménez# | .2422 | 2021-2031 | |
| 53 | George Sherrill | .2425 | 2005-2021 | |
| 54 | Dave Pownall | .2426 | 2014-2027 | |
| 55 | Carlos Zambrano | .2427 | 2001-2019 | |
| 55 | Angel Miranda | .2427 | 1993-2006 | |
| 57 | Eddie Morgan* | .2428 | 2005-2019 | |
| 58 | Joba Chamberlain | .2429 | 2012-2027 | |
| 59 | Garth Vaughn | .2441 | 2008-2020 | |
| 60 | Aaron Sele* | .2444 | 1993-2006 | |
| 60 | Kyle Jones | .2444 | 2016-2025 | |
| 60 | Dwight Tucker | .2444 | 2011-2027 | |
| 63 | Major Pixel | .2448 | 2007-2021 | |
| 63 | Freddy Castellanos | .2448 | 2008-2018 | |
| 65 | Manuel Vázquez# | .2453 | 2024-2031 | |
| 66 | Allen Bailey | .2454 | 2011-2023 | |
| 66 | Heath Bell | .2454 | 2004-2021 | |
| 68 | A J Burnett | .2456 | 1999-2010 | |
| 68 | Will Terry | .2456 | 2014-2025 | |
| 70 | Scott Randall | .2458 | 2003-2020 | |
| 71 | Ian Richardson | .2459 | 2009-2019 | |
| 72 | Tim Lincecum | .2462 | 2009-2025 | |
| 73 | Steve Watts | .2464 | 2008-2021 | |
| 73 | Cole Hamels* | .2464 | 2007-2023 | |
| 73 | Tony Saunders | .2464 | 1997-2012 | |
| 76 | Kevin Schaefer | .2467 | 2012-2023 | |
| 77 | Ugueth Urbina | .2471 | 1995-2013 | |
| 77 | Victor Dunlap | .2471 | 2010-2020 | |
| 79 | Kelvim Escobar | .2473 | 1997-2018 | |
| 79 | Josh Johnson | .2473 | 2010-2018 | |
| 81 | Jose Acevedo | .2474 | 2002-2013 | |
| 82 | Shelby Miller | .2475 | 2016-2027 | |
| 82 | Jorge Enríquez# | .2475 | 2020-2031 | |
| 82 | Dorian Bunch# | .2475 | 2022-2031 | |
| 85 | Roger Bailey | .2476 | 2003-2014 | |
| 86 | António Ortíz | .2478 | 2002-2011 | |
| 87 | Brian Wilson | .2483 | 2007-2021 | |
| 88 | Jesús Bravo# | .2487 | 2026-2031 | |
| 89 | Kevin Walters | .2488 | 2003-2015 | |
| 90 | Bob Clark | .2489 | 2001-2015 | |
| 91 | Cam Herb | .2492 | 2009-2017 | |
| 92 | Diego Madraso | .2493 | 2005-2012 | |
| 93 | Eric Hurley | .2495 | 2007-2020 | |
| 93 | Jarrod Schmidt | .2495 | 2018-2028 | |
| 93 | Pedro Montáñez | .2495 | 2002-2010 | |
| 96 | John Smoltz | .2497 | 1988-2003 | |
| 96 | Paul Phelps | .2497 | 2014-2026 | |
| 98 | Eduard Fotachi# | .2498 | 2019-2031 | |
| 99 | Andy Ashby | .2500 | 1991-2002 | |
| 100 | Felix Hernandez | .2501 | 2009-2020 |
