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| Position | Top player | Team ranking | Top prospect | Organizational ranking | Overall ranking |
|---|---|---|---|---|---|
| Catchers | Jason Varitek | 25th | Tony Delgado | Tied for 22nd | 25th |
| First Basemen | Adam Dunn | 4th | John Bowker | 7th | 3rd |
| Second Basemen | Ryan Theriot | 25th | Robert Andino | 7th | 23rd |
| Third Basemen | Edwin Encarnacion | 7th | Travis Metcalf | 14th | 8th |
| Shortstops | Nomar Garciaparra | 8th | Javy Hernandez | 18th | 8th |
| Left Fielders | Garret Anderson | 20th | Billy Butler | 19th | 22nd |
| Center Fielders | Jerry Hairston Jr. | 22nd | Alex Torres | 7th | 21st |
| Right Fielders | Bobby Kielty | 23rd | Santos Romerez | 5th | 21st |
| Starting Pitchers | Rich Harden | 25th | Matt Cain | 26th | 28th |
| Relievers | J.C. Romero | 22nd | Nate Moore | 26th | 22nd |
| Closers | Kyle Farnsworth | 5th | Manny Parra | 7th | 5th |
