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| Name | W | L | SV | ERA | G | GS | IP | HA | R | ER | HR | BB | K | WHIP | OAVG | BABIP | WAR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Antonio Osuna RP | 7 | 0 | 0 | 0.34 | 18 | 0 | 26.2 | 10 | 1 | 1 | 0 | 8 | 22 | 0.67 | .114 | .152 | 0.7 |
| Keith Foulke CL | 2 | 4 | 44 | 2.44 | 66 | 0 | 73.2 | 53 | 22 | 20 | 4 | 16 | 75 | 0.94 | .191 | .247 | 3.7 |
| Jimmy Gobble RP | 5 | 2 | 4 | 2.51 | 56 | 0 | 86.0 | 62 | 24 | 24 | 13 | 24 | 64 | 1.00 | .197 | .203 | 0.3 |
| Matt Lindstrom RP | 6 | 2 | 2 | 2.60 | 49 | 0 | 69.1 | 41 | 20 | 20 | 10 | 28 | 64 | 1.00 | .168 | .182 | 0.3 |
| Andy Pettitte SP | 8 | 3 | 0 | 2.99 | 15 | 15 | 87.1 | 80 | 32 | 29 | 10 | 19 | 70 | 1.13 | .242 | .277 | 2.0 |
| Azael Alvarez SP | 6 | 3 | 0 | 3.22 | 27 | 27 | 145.1 | 109 | 57 | 52 | 15 | 66 | 135 | 1.20 | .210 | .251 | 2.4 |
| Adam Wainwright SP | 17 | 9 | 0 | 3.57 | 33 | 33 | 216.2 | 190 | 87 | 86 | 30 | 46 | 164 | 1.09 | .235 | .259 | 3.9 |
| Cliff Politte RP | 7 | 1 | 1 | 3.61 | 63 | 0 | 82.1 | 75 | 34 | 33 | 10 | 23 | 63 | 1.19 | .244 | .277 | 0.9 |
| Jason Scobie RP | 10 | 8 | 0 | 3.64 | 32 | 32 | 185.1 | 143 | 78 | 75 | 26 | 76 | 138 | 1.18 | .214 | .230 | 1.5 |
| Scott Stewart RP | 6 | 3 | 1 | 3.65 | 41 | 0 | 44.1 | 31 | 19 | 18 | 8 | 13 | 37 | 0.99 | .193 | .198 | -0.1 |
| Horacio Ramirez SP | 1 | 0 | 0 | 4.15 | 3 | 0 | 8.2 | 10 | 5 | 4 | 1 | 7 | 5 | 1.96 | .294 | .321 | -0.1 |
| Kirk Rueter RP | 6 | 4 | 0 | 4.34 | 31 | 12 | 95.1 | 93 | 46 | 46 | 13 | 29 | 35 | 1.28 | .250 | .246 | 0.2 |
| John Wasdin RP | 4 | 4 | 5 | 4.41 | 36 | 0 | 49.0 | 43 | 24 | 24 | 6 | 15 | 34 | 1.18 | .235 | .259 | 0.4 |
| Ryan Rupe SP | 9 | 15 | 0 | 4.47 | 33 | 33 | 193.1 | 190 | 100 | 96 | 42 | 55 | 158 | 1.27 | .253 | .267 | 0.6 |
| Troy Pickford SP | 0 | 1 | 0 | 6.23 | 3 | 2 | 13.0 | 16 | 10 | 9 | 4 | 7 | 6 | 1.77 | .302 | .279 | -0.3 |
| John Thomson SP | 0 | 1 | 0 | 6.38 | 5 | 5 | 24.0 | 32 | 17 | 17 | 2 | 8 | 18 | 1.67 | .330 | .380 | 0.5 |
| Edgar Huerta RP | 2 | 3 | 0 | 6.86 | 31 | 0 | 42.0 | 43 | 35 | 32 | 7 | 23 | 41 | 1.57 | .259 | .305 | -0.4 |
| Trey Moore SP | 2 | 0 | 0 | 6.89 | 5 | 3 | 15.2 | 17 | 12 | 12 | 1 | 17 | 10 | 2.17 | .274 | .314 | -0.2 |
| Brandon League RP | 0 | 1 | 0 | 9.82 | 7 | 0 | 11.0 | 16 | 12 | 12 | 4 | 4 | 7 | 1.82 | .348 | .343 | -0.4 |
