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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Júlio Sánchez | 155 | 2006-2021 | |
| 2 | Curt Rice | 109 | 2019-2024 | |
| 3 | Anthony Rizzo | 91 | 2012-2021 | |
| 4 | Ángel González | 89 | 2010-2013 | |
| 4 | John Wells | 89 | 2016-2019 | |
| 6 | Felipe Costa# | 88 | 2026-2030 | |
| 7 | Danny Buckley | 77 | 2010-2018 | |
| 8 | Santiago Ibarra | 70 | 2018-2019 | |
| 8 | Juan Montoya# | 70 | 2022-2022 | |
| 8 | Raúl Ortíz | 70 | 2015-2020 | |
| 11 | Mototsune Iitsuka# | 69 | 2030-2031 | |
| 12 | Dave Staton | 68 | 1993-2001 | |
| 13 | Matt Olson# | 65 | 2022-2024 | |
| 13 | Tom Parkinson# | 65 | 2020-2020 | |
| 15 | Ron Perry | 64 | 2013-2013 | |
| 16 | Sancho Gallegos# | 63 | 2027-2028 | |
| 16 | Josh MacCloy# | 63 | 2021-2026 | |
| 18 | Jonathan Bryant | 61 | 2018-2024 | |
| 19 | John Ward# | 60 | 2020-2021 | |
| 19 | Tom Young | 60 | 2015-2016 | |
| 21 | Ralph Mitchell | 58 | 2017-2023 | |
| 22 | Jack Stevens | 56 | 2022-2023 | |
| 22 | Curtis Walsh | 56 | 2014-2014 | |
| 24 | Lance Burrell# | 54 | 2022-2028 | |
| 24 | Bryan Christensen# | 54 | 2021-2028 | |
| 24 | Bucky Jacobsen* | 54 | 2005-2005 | |
| 24 | Les Westacott# | 54 | 2027-2029 | |
| 28 | Ángel Baca | 52 | 2009-2021 | |
| 28 | Michael Little | 52 | 2009-2018 | |
| 28 | José Rodríguez | 52 | 2014-2020 | |
| 28 | Michael Rogers | 52 | 2015-2016 | |
| 32 | Armando Cortés# | 51 | 2029-2031 | |
| 32 | Rhys Hoskins | 51 | 2021-2021 | |
| 34 | Prince Fielder | 50 | 2005-2016 | |
| 34 | Duncan Kenselaar# | 50 | 2027-2031 | |
| 34 | Kurt Spencer | 50 | 2015-2020 | |
| 37 | Jim Stanley | 49 | 2022-2025 | |
| 38 | Don Anderson# | 48 | 2020-2021 | |
| 39 | Oliver Cantú | 47 | 2007-2019 | |
| 39 | Greg Pirkl | 47 | 1994-2004 | |
| 39 | Roberto Álvarez | 47 | 2000-2014 | |
| 42 | Grady MacIntosh# | 46 | 2024-2029 | |
| 43 | Marcos Armas | 44 | 1993-2001 | |
| 43 | Sidney Curry# | 44 | 2016-2018 | |
| 43 | Andrew Johnson | 44 | 2018-2018 | |
| 46 | Al Hammond# | 43 | 2024-2024 | |
| 47 | Ted Ball# | 42 | 2024-2028 | |
| 47 | Martín Cortéz | 42 | 2002-2013 | |
| 47 | Joseph Moore# | 42 | 2027-2028 | |
| 47 | George Silcock | 42 | 2018-2023 | |
| 51 | Pete Alonso# | 41 | 2020-2020 | |
| 51 | Guy Arens# | 41 | 2028-2031 | |
| 51 | Esteban Gallardo | 41 | 2008-2014 | |
| 51 | Colt Jordan | 41 | 2014-2015 | |
| 51 | Sam McElroy# | 41 | 2023-2026 | |
| 56 | Trent Benjamin | 40 | 2010-2010 | |
| 56 | Joe Terry# | 40 | 2029-2030 | |
| 58 | Ken Curtis | 39 | 2010-2014 | |
| 58 | Roger Evans# | 39 | 2020-2022 | |
| 58 | Chris Sharp | 39 | 2016-2016 | |
| 58 | Michael Townsend# | 39 | 2020-2028 | |
| 62 | Tim Finley | 38 | 2018-2018 | |
| 62 | Chris Jones | 38 | 2020-2020 | |
| 62 | Luke Lowe# | 38 | 2023-2024 | |
| 62 | Timothy Rogers | 38 | 2015-2015 | |
| 62 | Jesús Salgado# | 38 | 2029-2030 | |
| 62 | Owen Spring | 38 | 2011-2014 | |
| 68 | Ben Gregory | 37 | 2018-2021 | |
| 68 | Arturo Vera# | 37 | 2025-2025 | |
| 70 | Don Davidson# | 36 | 2027-2029 | |
| 70 | Juan Méndez | 36 | 2007-2018 | |
| 70 | Drew Saunders# | 36 | 2023-2028 | |
| 70 | Dennis Simpson# | 36 | 2021-2022 | |
| 74 | Mike Dunn | 35 | 2018-2019 | |
| 74 | Edmund Ferris | 35 | 2003-2005 | |
| 74 | Miguel Angel García# | 35 | 2030-2030 | |
| 74 | Manuel López# | 35 | 2028-2029 | |
| 74 | Eduardo Rivera# | 35 | 2023-2023 | |
| 74 | Víctor Rocha# | 35 | 2030-2031 | |
| 74 | Josh Wilson | 35 | 2008-2013 | |
| 81 | Nathan Barber | 34 | 2016-2017 | |
| 81 | John Hampton | 34 | 2014-2018 | |
| 81 | Mike Morrow | 34 | 2020-2020 | |
| 81 | Alberto Pérez | 34 | 2000-2002 | |
| 85 | Mike Glendenning# | 33 | 2030-2031 | |
| 85 | Lee Orr# | 33 | 2025-2026 | |
| 87 | Miguel Aguilar# | 32 | 2030-2031 | |
| 87 | Ben Anderson# | 32 | 2022-2029 | |
| 87 | Horace Hutchinson | 32 | 2020-2020 | |
| 87 | Costanzo Rossano | 32 | 2000-2012 | |
| 91 | Harry Ford | 31 | 2007-2010 | |
| 91 | Ken Jackson | 31 | 2017-2017 | |
| 91 | Gary Miner# | 31 | 2021-2022 | |
| 91 | Hisanobu Yoshikawa# | 31 | 2026-2027 | |
| 95 | Aliyy bin Kadin | 30 | 2010-2012 | |
| 95 | César Chávez# | 30 | 2017-2017 | |
| 95 | Ambrose Corona | 30 | 2016-2023 | |
| 95 | Raúl Díaz | 30 | 2013-2013 | |
| 95 | Dong-kyoon Pae# | 30 | 2029-2029 | |
| 95 | Kian Rymer# | 30 | 2031-2031 |
