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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K9 | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Gilberto Martínez# | 17.79 | 2029 | |
| 2 | Gilberto Martínez# | 16.55 | 2028 | |
| 3 | Gilberto Martínez# | 15.53 | 2027 | |
| 4 | Gilberto Martínez# | 14.85 | 2030 | |
| 5 | Archie Esparza# | 14.84 | 2027 | |
| 6 | Archie Esparza# | 14.36 | 2028 | |
| 7 | Archie Esparza# | 13.33 | 2029 | |
| 8 | Fernando Montero# | 13.13 | 2030 | |
| 9 | Randy D Johnson | 12.74 | 1997 | |
| 10 | Archie Esparza# | 12.56 | 2026 | |
| 11 | Bill Gill# | 12.23 | 2026 | |
| 12 | Rick Ankiel | 12.17 | 1999 | |
| 13 | Randy D Johnson | 12.08 | 1994 | |
| 14 | Kerry Wood | 11.97 | 1998 | |
| 15 | Bill Gill# | 11.88 | 2025 | |
| 16 | Randy D Johnson | 11.87 | 1996 | |
| 17 | Rick Snow# | 11.79 | 2028 | |
| 18 | Julián Rosa# | 11.74 | 2021 | |
| 19 | Kerry Wood | 11.69 | 1999 | |
| 20 | Bo Valadez# | 11.64 | 2030 | |
| 21 | Jorge Enríquez# | 11.55 | 2022 | |
| 22 | James Ryan# | 11.52 | 2021 | |
| 23 | Kerry Wood | 11.50 | 2003 | |
| 24 | James Ryan# | 11.49 | 2023 | |
| 25 | Randy D Johnson | 11.48 | 1990 | |
| 25 | Pedro López# | 11.48 | 2020 | |
| 25 | Rick Snow# | 11.48 | 2029 | |
| 28 | Bob Jenkins* | 11.45 | 2014 | |
| 29 | Randy D Johnson | 11.42 | 1991 | |
| 29 | James Ryan# | 11.42 | 2020 | |
| 31 | Jorge Enríquez# | 11.39 | 2027 | |
| 31 | Kerry Wood | 11.39 | 2002 | |
| 33 | Jorge Enríquez# | 11.37 | 2021 | |
| 34 | Mark Prior* | 11.35 | 2002 | |
| 34 | Gilberto Martínez# | 11.35 | 2026 | |
| 36 | Randy D Johnson | 11.32 | 1998 | |
| 37 | Rick Ankiel | 11.31 | 2000 | |
| 38 | Mark Prior* | 11.22 | 2003 | |
| 39 | Bill Gill# | 11.18 | 2027 | |
| 40 | James Ryan# | 11.17 | 2022 | |
| 41 | Joe Sparks | 11.15 | 2008 | |
| 42 | Ronald Moyer# | 11.14 | 2024 | |
| 43 | Daron Maddox | 11.10 | 2020 | |
| 44 | Gilberto Martínez# | 11.08 | 2031 | |
| 44 | Matt Beech | 11.08 | 2001 | |
| 46 | José Torres# | 11.02 | 2030 | |
| 47 | Kerry Wood | 11.01 | 2006 | |
| 47 | Ugueth Urbina | 11.01 | 1997 | |
| 49 | Rick Snow# | 11.00 | 2027 | |
| 50 | Rick Snow# | 10.90 | 2026 | |
| 51 | Jorge Enríquez# | 10.89 | 2023 | |
| 52 | Scott Kazmir | 10.87 | 2008 | |
| 53 | Jorge Enríquez# | 10.85 | 2024 | |
| 54 | Bob Jenkins* | 10.84 | 2013 | |
| 55 | Bob Jenkins* | 10.82 | 2016 | |
| 56 | Fernando Montero# | 10.79 | 2029 | |
| 57 | Archie Esparza# | 10.78 | 2031 | |
| 58 | Bill Gill# | 10.77 | 2024 | |
| 58 | Michael Hood | 10.77 | 2003 | |
| 60 | Bob Jenkins* | 10.70 | 2015 | |
| 61 | Joe Sparks | 10.69 | 2009 | |
| 61 | Randy D Johnson | 10.69 | 1992 | |
| 63 | Jorge Enríquez# | 10.65 | 2028 | |
| 64 | Joe Sparks | 10.62 | 2011 | |
| 65 | Jorge Enríquez# | 10.60 | 2029 | |
| 66 | Scott Sanders | 10.57 | 1996 | |
| 67 | Bill Gill# | 10.53 | 2023 | |
| 67 | Mark Prior* | 10.53 | 2006 | |
| 69 | Victor Dunlap | 10.50 | 2010 | |
| 70 | James Ryan# | 10.49 | 2024 | |
| 71 | Jorge Enríquez# | 10.47 | 2025 | |
| 72 | Vicente Maldonado# | 10.44 | 2028 | |
| 73 | Roger Clemens* | 10.41 | 1994 | |
| 74 | Bob Jenkins* | 10.38 | 2012 | |
| 75 | Ugueth Urbina | 10.37 | 1998 | |
| 75 | Gabe Johnson | 10.37 | 2020 | |
| 77 | Hideo Nomo | 10.36 | 1997 | |
| 78 | Scott Kazmir | 10.32 | 2009 | |
| 79 | Eduard Fotachi# | 10.28 | 2022 | |
| 80 | Manuel Vázquez# | 10.26 | 2026 | |
| 81 | Ronald Moyer# | 10.25 | 2028 | |
| 81 | Bob Jenkins* | 10.25 | 2021 | |
| 81 | Rick Ankiel | 10.25 | 2001 | |
| 84 | Dwight Tucker | 10.24 | 2020 | |
| 85 | Tito Smith# | 10.23 | 2023 | |
| 86 | Cliff Cuervo# | 10.22 | 2021 | |
| 86 | Hideo Nomo | 10.22 | 1996 | |
| 86 | Matthew Trantham | 10.22 | 2020 | |
| 89 | Ugueth Urbina | 10.21 | 1999 | |
| 90 | Javier Vazquez* | 10.19 | 2002 | |
| 91 | Scott Sanders | 10.17 | 1999 | |
| 91 | Scott Sanders | 10.17 | 2001 | |
| 93 | Roger Clemens* | 10.15 | 1993 | |
| 93 | Victor Dunlap | 10.15 | 2012 | |
| 93 | Bob Jenkins* | 10.15 | 2017 | |
| 96 | Hideo Nomo | 10.14 | 2000 | |
| 97 | Yu Darvish | 10.12 | 2015 | |
| 98 | Mark Prior* | 10.11 | 2005 | |
| 98 | Kyle Jones | 10.11 | 2019 | |
| 100 | Jorge Enríquez# | 10.10 | 2030 |
