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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | OOPS | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | John Wood# | .4609 | 2029-2031 | |
| 2 | Matt J Miller | .4914 | 2003-2016 | |
| 3 | Dan Woods# | .4949 | 2023-2031 | |
| 4 | Alfredo Gómez# | .5008 | 2028-2031 | |
| 5 | Luis Anguiana# | .5294 | 2026-2031 | |
| 6 | Heath Bell | .5307 | 2004-2021 | |
| 7 | Paul Hale# | .5389 | 2020-2031 | |
| 8 | Roger Bailey | .5446 | 2003-2014 | |
| 9 | Jason Dickson | .5455 | 1997-2006 | |
| 10 | Gilberto Martínez# | .5632 | 2025-2031 | |
| 11 | Roger Clemens* | .5690 | 1984-2006 | |
| 12 | Brad Cochran | .5702 | 2019-2027 | |
| 13 | Bryan Kent# | .5717 | 2025-2031 | |
| 14 | Bob Schultz | .5720 | 2013-2022 | |
| 15 | Dan White | .5742 | 2012-2021 | |
| 16 | António Ortíz | .5776 | 2002-2011 | |
| 17 | Francisco Ramírez# | .5777 | 2017-2030 | |
| 18 | Ignacio Reyes# | .5780 | 2028-2031 | |
| 19 | Ian Kennedy | .5786 | 2010-2019 | |
| 19 | Jonathan Papelbon | .5786 | 2008-2021 | |
| 21 | Joel Zumaya | .5808 | 2011-2023 | |
| 22 | Ryan Arnold | .5893 | 2012-2021 | |
| 23 | A J Burnett | .5904 | 1999-2010 | |
| 24 | Chad Qualls | .5952 | 2006-2020 | |
| 25 | Clifton Jackson# | .6012 | 2024-2029 | |
| 26 | Randy D Johnson | .6022 | 1988-2003 | |
| 27 | Ronald Moyer# | .6044 | 2023-2031 | |
| 28 | Eduardo Vázquez# | .6068 | 2023-2030 | |
| 29 | Charlie Frohwirth | .6084 | 2012-2024 | |
| 30 | Carlos Jiménez# | .6109 | 2021-2031 | |
| 31 | Jason Ellis | .6114 | 2013-2027 | |
| 32 | Héctor Bernal# | .6140 | 2024-2031 | |
| 33 | Duane Wilson | .6142 | 2008-2020 | |
| 34 | Adrian Ackermann | .6165 | 2014-2022 | |
| 35 | John Christensen | .6169 | 2015-2024 | |
| 36 | Jose A Nunez | .6175 | 2001-2012 | |
| 37 | Kevin Walters | .6191 | 2003-2015 | |
| 38 | Daniel Patterson | .6206 | 2017-2029 | |
| 39 | Thomas Rice# | .6210 | 2017-2031 | |
| 40 | Dennis Redden# | .6224 | 2029-2031 | |
| 41 | Raúl López | .6232 | 2000-2016 | |
| 42 | Henry Moss# | .6249 | 2019-2029 | |
| 43 | Jerry Patterson | .6263 | 2002-2015 | |
| 44 | Erik Bedard | .6265 | 2004-2013 | |
| 45 | Joakim Soria | .6286 | 2012-2022 | |
| 46 | Mark Prior* | .6307 | 2002-2016 | |
| 47 | Amdre Nova# | .6314 | 2030-2031 | |
| 48 | Scott Sanders | .6331 | 1993-2007 | |
| 49 | Santiago Herrera | .6378 | 2000-2018 | |
| 50 | Jon Lester | .6379 | 2008-2021 | |
| 51 | Justin Thompson | .6380 | 2016-2026 | |
| 52 | Barry Zito | .6392 | 2000-2014 | |
| 53 | Daron Maddox | .6401 | 2015-2027 | |
| 54 | Eddie Morgan* | .6429 | 2005-2019 | |
| 55 | David Price | .6433 | 2011-2019 | |
| 56 | Jeff Shoemaker# | .6451 | 2025-2031 | |
| 57 | Tim Pulliam# | .6470 | 2026-2031 | |
| 58 | Roy Halladay* | .6472 | 1998-2014 | |
| 59 | Javier Vazquez* | .6474 | 1998-2013 | |
| 60 | Jeff Samardzija | .6486 | 2009-2021 | |
| 61 | Cisco Castellanos# | .6487 | 2025-2031 | |
| 62 | Zack Greinke* | .6488 | 2005-2020 | |
| 63 | Matt Morris | .6491 | 1997-2005 | |
| 64 | Raúl Mateo# | .6505 | 2026-2031 | |
| 65 | Máximo Sánchez | .6527 | 2015-2025 | |
| 66 | Stan Combs# | .6535 | 2023-2031 | |
| 67 | Felix Hernandez | .6542 | 2009-2020 | |
| 68 | Brett Tomko | .6563 | 1997-2004 | |
| 69 | Brandon Webb* | .6566 | 2004-2024 | |
| 70 | Ken Brandon | .6578 | 2019-2029 | |
| 71 | Eric Hurley | .6596 | 2007-2020 | |
| 72 | Adelphos Papademetriou | .6601 | 2002-2011 | |
| 73 | Josh Fogg | .6605 | 2001-2012 | |
| 74 | José Torres# | .6614 | 2026-2031 | |
| 74 | Allen Bailey | .6614 | 2011-2023 | |
| 76 | Rick Cederberg# | .6616 | 2025-2031 | |
| 77 | Gabe Johnson | .6644 | 2019-2028 | |
| 78 | Jake Peavy | .6647 | 2002-2017 | |
| 79 | Jorge Enríquez# | .6648 | 2020-2031 | |
| 80 | Hipolito Pichardo | .6653 | 1992-2008 | |
| 81 | Dave Pownall | .6670 | 2014-2027 | |
| 82 | Dusty Massey# | .6675 | 2019-2025 | |
| 83 | Bob Jenkins* | .6727 | 2008-2023 | |
| 84 | Leo Erickson# | .6732 | 2022-2029 | |
| 85 | Shelby Miller | .6744 | 2016-2027 | |
| 86 | Micah Olson# | .6752 | 2016-2031 | |
| 87 | William Pierce# | .6755 | 2025-2031 | |
| 88 | Kevin Schaefer | .6764 | 2012-2023 | |
| 89 | Chad Billingsley | .6776 | 2008-2024 | |
| 90 | CC Sabathia* | .6777 | 2001-2019 | |
| 91 | Eldon Hernández | .6779 | 2018-2026 | |
| 92 | Ugueth Urbina | .6782 | 1995-2013 | |
| 93 | David Nied* | .6790 | 1992-2009 | |
| 94 | Aaron Sele* | .6812 | 1993-2006 | |
| 95 | Carlos Cotter | .6833 | 2008-2020 | |
| 96 | Ismael Valdez* | .6836 | 1994-2010 | |
| 97 | Jorge Flores# | .6838 | 2025-2031 | |
| 98 | Cole Hamels* | .6840 | 2007-2023 | |
| 99 | Archie Esparza# | .6846 | 2025-2031 | |
| 100 | Chris Sharp# | .6847 | 2021-2031 |
