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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | OAVG | YEAR | Open Postseason Career Leaderboard |
|---|---|---|---|---|
| 1 | Luis Anguiana# | .1000 | 2030 | |
| 2 | Heath Bell | .1094 | 2009 | |
| 3 | Manny Aybar | .1154 | 2005 | |
| 4 | Jeff Samardzija | .1356 | 2018 | |
| 5 | Dirk Von Hayhurst | .1373 | 2007 | |
| 6 | John Wood# | .1385 | 2029 | |
| 6 | Major Pixel | .1385 | 2019 | |
| 8 | Brandon Webb* | .1481 | 2008 | |
| 8 | Joakim Soria | .1481 | 2017 | |
| 10 | Clifton Jackson# | .1489 | 2025 | |
| 11 | Bob Jenkins* | .1500 | 2014 | |
| 12 | Brad Cochran | .1525 | 2022 | |
| 13 | Anthony Hunt | .1538 | 2019 | |
| 13 | Dan Woods# | .1538 | 2024 | |
| 15 | Jeff Samardzija | .1546 | 2017 | |
| 16 | Nathan Whalebelly | .1558 | 2016 | |
| 17 | Jason Ellis | .1565 | 2020 | |
| 18 | Henry Moss# | .1569 | 2025 | |
| 19 | Josh Fogg | .1571 | 2003 | |
| 20 | Jake Peavy | .1579 | 2010 | |
| 20 | Diego Madraso | .1579 | 2006 | |
| 22 | Roger Bailey | .1589 | 2003 | |
| 23 | Tito Smith# | .1600 | 2025 | |
| 24 | Eric Hurley | .1618 | 2013 | |
| 25 | Alfredo Gómez# | .1646 | 2029 | |
| 26 | Kumar Rocker# | .1667 | 2022 | |
| 26 | Brandon Webb* | .1667 | 2009 | |
| 26 | Andrew Bailey | .1667 | 2012 | |
| 26 | Madison Bumgarner | .1667 | 2024 | |
| 26 | Gilberto Martínez# | .1667 | 2029 | |
| 31 | John Smoltz | .1681 | 1989 | |
| 32 | Eddie Morgan* | .1690 | 2014 | |
| 33 | Scott Sanders | .1702 | 2001 | |
| 34 | Tim Lincecum | .1711 | 2015 | |
| 35 | Dan Woods# | .1714 | 2028 | |
| 36 | Aaron Sele* | .1719 | 2003 | |
| 37 | Johan Santana | .1724 | 2014 | |
| 37 | Zack Greinke* | .1724 | 2013 | |
| 39 | Dan White | .1728 | 2019 | |
| 40 | Matt J Miller | .1731 | 2005 | |
| 41 | Raúl Mateo# | .1739 | 2030 | |
| 42 | Javier Vazquez* | .1743 | 2006 | |
| 43 | Roy Ward | .1746 | 2022 | |
| 43 | Ronald Moyer# | .1746 | 2031 | |
| 45 | Steve Karsay | .1780 | 1995 | |
| 46 | Adelphos Papademetriou | .1781 | 2005 | |
| 47 | Shelby Miller | .1786 | 2022 | |
| 48 | David Price | .1792 | 2013 | |
| 49 | Bud Smith | .1803 | 2004 | |
| 49 | Máximo Sánchez | .1803 | 2023 | |
| 49 | Eduardo Vázquez# | .1803 | 2025 | |
| 52 | Ugueth Urbina | .1818 | 1999 | |
| 52 | Roger Clemens* | .1818 | 1990 | |
| 54 | Amdre Nova# | .1826 | 2031 | |
| 55 | Tim Pulliam# | .1833 | 2029 | |
| 55 | Javier Vazquez* | .1833 | 2003 | |
| 57 | Bob Jenkins* | .1838 | 2018 | |
| 58 | George Connolly# | .1848 | 2022 | |
| 59 | Benny Howard# | .1852 | 2023 | |
| 59 | Paul Hale# | .1852 | 2026 | |
| 61 | Jerry Patterson | .1855 | 2012 | |
| 62 | Gerardo Domínguez# | .1864 | 2031 | |
| 63 | Javier Vazquez* | .1871 | 2005 | |
| 64 | Daron Maddox | .1872 | 2017 | |
| 65 | Chad Billingsley | .1875 | 2011 | |
| 65 | Roger Clemens* | .1875 | 1997 | |
| 67 | Eddie Morgan* | .1883 | 2011 | |
| 68 | Jim Anderson# | .1884 | 2022 | |
| 68 | Jack Flaherty# | .1884 | 2031 | |
| 68 | Carlos Jiménez# | .1884 | 2026 | |
| 71 | Ken Brandon | .1892 | 2021 | |
| 71 | Eric Hurley | .1892 | 2014 | |
| 73 | Roger Clemens* | .1895 | 1987 | |
| 73 | Aaron Sele* | .1895 | 1998 | |
| 75 | José Torres# | .1898 | 2030 | |
| 76 | Javier Vazquez* | .1900 | 2001 | |
| 76 | Tim Pulliam# | .1900 | 2028 | |
| 78 | Lee Myers# | .1902 | 2026 | |
| 79 | Daniel Patterson | .1908 | 2025 | |
| 80 | Tommy Austin | .1909 | 2017 | |
| 80 | Roy Halladay* | .1909 | 2002 | |
| 82 | Juan Guzman* | .1912 | 1994 | |
| 82 | Ignacio Reyes# | .1912 | 2028 | |
| 84 | Luis Anguiana# | .1923 | 2028 | |
| 85 | Dennis Redden# | .1935 | 2031 | |
| 85 | Allen Bailey | .1935 | 2016 | |
| 85 | Frank Larkin | .1935 | 2004 | |
| 85 | Joey Hamilton | .1935 | 2001 | |
| 89 | CC Sabathia* | .1939 | 2008 | |
| 90 | Jerry Patterson | .1947 | 2009 | |
| 91 | Randy D Johnson | .1951 | 1992 | |
| 92 | Cole Hamels* | .1955 | 2013 | |
| 93 | Eric Brennan# | .1961 | 2020 | |
| 94 | Kevin Schaefer | .1963 | 2017 | |
| 95 | Bryan Kent# | .1967 | 2027 | |
| 96 | Eddie Morgan* | .1972 | 2016 | |
| 97 | Malcolm Zegwaard | .1975 | 2014 | |
| 98 | Randy D Johnson | .1978 | 1991 | |
| 99 | John Greer# | .1979 | 2025 | |
| 100 | Theron Prince | .1980 | 2009 |
