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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | RBI | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Pepe Mendoza* | 1359 | 2007-2022 | |
| 2 | Prakoso Prawiranega* | 1161 | 2007-2024 | |
| 3 | Cisco Hernández | 1144 | 2006-2020 | |
| 4 | Red Turner# | 1119 | 2018-2031 | |
| 5 | Troy Glaus | 1110 | 1998-2011 | |
| 6 | Corey Koskie* | 1100 | 1998-2012 | |
| 7 | Bo Greene | 1074 | 2008-2027 | |
| 8 | Dave Nelson | 1027 | 2007-2025 | |
| 9 | Edgardo Estrada | 1003 | 2010-2022 | |
| 10 | Peter Donaldson# | 992 | 2015-2031 | |
| 11 | Michael Cuddyer | 988 | 2001-2013 | |
| 12 | Jim Thome* | 961 | 1991-2006 | |
| 13 | Joshua Stevens# | 930 | 2020-2031 | |
| 14 | Albert Pujols* | 904 | 2001-2020 | |
| 15 | Stanley Price | 893 | 2016-2028 | |
| 16 | Adrian Beltre | 821 | 1998-2009 | |
| 17 | Eric Chavez | 798 | 1998-2008 | |
| 18 | Kyle Seager | 752 | 2009-2023 | |
| 19 | Randy Walton | 748 | 2016-2025 | |
| 20 | Dave Hansen | 733 | 1990-2001 | |
| 21 | John Bishop | 724 | 2016-2025 | |
| 22 | Justin Leone | 722 | 2005-2017 | |
| 23 | Eduardo Perez | 705 | 1993-2002 | |
| 24 | Rusty Klein | 687 | 2014-2025 | |
| 25 | Mike Lowell | 668 | 1998-2007 | |
| 26 | Evan Longoria | 659 | 2008-2020 | |
| 27 | Warren Allen | 654 | 2012-2020 | |
| 27 | Collin Combs# | 654 | 2024-2031 | |
| 29 | Luis Sánchez# | 643 | 2021-2031 | |
| 30 | Scott Rolen | 630 | 1996-2006 | |
| 31 | Aramis Ramirez | 629 | 2001-2011 | |
| 32 | Nolan Arenado# | 624 | 2024-2031 | |
| 33 | Russ Davis | 622 | 1994-2005 | |
| 34 | Bill R Mueller | 617 | 1996-2005 | |
| 35 | Mike Lamb | 614 | 2000-2009 | |
| 36 | Pablo Sandoval | 611 | 2007-2019 | |
| 37 | Butch Huskey | 609 | 1995-2006 | |
| 38 | Devin Brown | 605 | 2015-2022 | |
| 39 | Mark Knight | 582 | 2017-2030 | |
| 40 | Hank Blalock | 580 | 2002-2013 | |
| 41 | Freddie Anderson* | 573 | 2008-2021 | |
| 42 | Nick Glenn# | 552 | 2022-2031 | |
| 43 | Mark Moore | 532 | 2012-2026 | |
| 44 | Edmund Mueller | 529 | 2013-2028 | |
| 45 | Gary Anderson# | 525 | 2021-2031 | |
| 46 | Russell Branyan | 513 | 1998-2005 | |
| 47 | Aaron Boone | 511 | 1997-2008 | |
| 48 | George Glover | 510 | 2016-2026 | |
| 48 | Doug Stewart | 510 | 2016-2029 | |
| 50 | Dale Stevenson# | 508 | 2015-2031 | |
| 51 | Mike Busch | 504 | 1995-2002 | |
| 52 | Cal Beason | 503 | 2017-2027 | |
| 53 | Luis A Gonzalez | 499 | 2004-2013 | |
| 53 | Greg Norton | 499 | 1996-2006 | |
| 55 | Rob Heater# | 488 | 2022-2031 | |
| 56 | Rod Neely | 485 | 2012-2019 | |
| 57 | José Sánchez | 483 | 2004-2012 | |
| 58 | Joe Randa | 475 | 1995-2008 | |
| 59 | Vic Alexander# | 464 | 2015-2027 | |
| 60 | Jason Graham | 461 | 2007-2018 | |
| 61 | Ricardo Maldonado# | 459 | 2021-2031 | |
| 62 | Masaharu Suzuki# | 453 | 2025-2031 | |
| 63 | Julius Johnston | 452 | 2020-2024 | |
| 64 | Cipriano Romero | 445 | 2019-2026 | |
| 65 | Ryan Marks | 443 | 2019-2028 | |
| 66 | Doug Smith | 431 | 2009-2014 | |
| 67 | Will Perry# | 417 | 2023-2028 | |
| 68 | Richard Lang | 416 | 2019-2023 | |
| 69 | Lawrence Conley# | 412 | 2024-2031 | |
| 70 | Jorge Ruíz# | 403 | 2024-2031 | |
| 71 | Dean Palmer | 399 | 1991-2000 | |
| 72 | Cristian Guzman | 390 | 1999-2012 | |
| 73 | Luis Ortiz | 381 | 1994-2003 | |
| 74 | Brendan Lumby# | 376 | 2026-2031 | |
| 74 | David O'Higgins | 376 | 2009-2013 | |
| 76 | Edwin Encarnacion | 375 | 2007-2017 | |
| 77 | Travis Fryman | 361 | 1990-2005 | |
| 78 | Daniel Murphy | 358 | 2008-2018 | |
| 79 | Eugene Andersen | 356 | 2018-2025 | |
| 80 | David Cornelius | 352 | 2000-2010 | |
| 81 | Randy Thomas | 350 | 2015-2022 | |
| 82 | Jose Vidro | 346 | 1997-2008 | |
| 83 | Felipe Crespo | 343 | 1996-2005 | |
| 84 | Jack Hartman# | 335 | 2022-2028 | |
| 85 | Júlio Ramos | 332 | 2002-2007 | |
| 86 | So Tran# | 331 | 2025-2029 | |
| 87 | Lynn Whitaker# | 318 | 2019-2025 | |
| 88 | Scott Cooper | 317 | 1990-2001 | |
| 89 | Zenos Logotheti | 316 | 2008-2014 | |
| 90 | Joey Durham# | 309 | 2020-2026 | |
| 91 | Erwin Parkhill | 308 | 2012-2018 | |
| 92 | Gavin Lux# | 307 | 2027-2031 | |
| 92 | Bill McDowell | 307 | 2012-2025 | |
| 94 | Alex Bregman# | 306 | 2022-2031 | |
| 94 | Nate Headley | 306 | 2009-2018 | |
| 96 | José Hernández | 301 | 2002-2008 | |
| 97 | Harlan Lawrence | 299 | 2019-2028 | |
| 97 | Andy Tracy | 299 | 2000-2008 | |
| 99 | Damion Easley | 295 | 1992-2004 | |
| 100 | Tim Larson | 294 | 2012-2020 |
